Npr1-regulated gene pathways contributing to cardiac hypertrophy and fibrosis
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چکیده
منابع مشابه
Npr1-regulated gene pathways contributing to cardiac hypertrophy and fibrosis.
The natriuretic peptides, atrial (ANP) and brain natriuretic peptide (BNP) are known to suppress cardiac hypertrophy and fibrosis. Both ANP and BNP exert their bioactivities through the Npr1 receptor, and Npr1 knockout mice (Npr1-/-) exhibit marked cardiac hypertrophy and fibrosis. In this study, we investigated which genes within the hypertrophic and fibrotic pathways are influenced by the lac...
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ژورنال
عنوان ژورنال: Journal of Molecular Endocrinology
سال: 2007
ISSN: 0952-5041,1479-6813
DOI: 10.1677/jme.1.02138